Research Paper Volume 15, Issue 13 pp 6400—6428

Figure 13. CDM subtypes associated with immunotherapeutic response predictors in TCGA-COAD datasets. (A) Tumor immune microenvironment analysis between CDM immune subtype A and subtype B by Microenvironment Cell Populations counter algorithm. (B–G) The association between CDM subtypes and immune cell infiltration; (B) for T cells; (C) for cytotoxic lymphocytes; (D) for neutrophils; (E) for B lineages; (F) for endothelial cells; (G) for fibroblasts. (H) Sankey diagram between the CDM subtypes and immune subtypes (C1-C6). (I–L) Relationship between the CDM subtypes and the immunotherapy data of PD1 and CTLA4 (I) for PD1 and CTLA4 negative expression; (J) for PD1 positive expression and CTLA4 negative expression; (K) for CTLA4 positive expression and PD1 negative expression; (L) for PD1 and CTLA4 negative expression.