Research Paper Volume 15, Issue 14 pp 6822—6833
S14G-Humanin ameliorates ovalbumin-induced airway inflammation in asthma mediated by inhibition of toll-like receptor 4 (TLR4) expression and the nuclear factor κ-B (NF-κB)/early growth response protein-1 (Egr-1) pathway
Figure 6. S14G-Humanin (HNG) prevented the activation of toll-like receptor 4/ nuclear factor κ-B (TLR4/NF-κB) and early growth response-1 (Egr-1) signaling. The levels of TLR4, p-NF-κB p65, and Egr-1 were measured using western blot analysis (**, P<0.01 vs. vehicle group; &, &&, P<0.05, 0.01 vs. asthma models).