Research Paper Volume 15, Issue 14 pp 6905—6920

Figure 4. Effect of PD, exo and exo-PD on survival, body weight, diarrhea rate, leukocyte change and behavior of mice after irradiation. (A) Effect of exo-PD on survival of mice after IR. (B, C) Differences in body weight changes and diarrhea rate of mice in different groups after IR. (D) Leukocyte changes on day 4 after irradiation in mice from different treatment groups. (E, F) Heat map and statistical results of the open field experiment in mice from two treatment groups, and black represents mice in IR group and gray represents mice in exo-PD group. PD solution, exosome solution and exo-PD solution were all injected intraperitoneally immediately after irradiation within half an hour. Data are presented as mean X¯±SEM, n = 10. Statistical plots with ^* as p < 0.05, ^** as p < 0.01 and ^*** as p < 0.001 indicate statistically significant differences between groups.