Research Paper Volume 15, Issue 16 pp 8501—8517
Xuebijing injection protects sepsis induced myocardial injury by mediating TLR4/NF-κB/IKKα and JAK2/STAT3 signaling pathways
Figure 2. Effects of XBJ on myocardial damage and inflammation in rat after CLP. (A) Pathological changes of myocardial tissues under HE staining (200×). (B) Representative echocardiographic images. (C, D) Quantification of LVFS and LVEF via echocardiography. (E–G) XBJ improved myocardial dysfunction in rat after CLP: Serum levels of LDH (E), CK (F) and cTnI (G) detected by automated biochemical analyzer. (H–J) XBJ alleviated the myocardial inflammation in rat after CLP: Serum levels of TNF-α (H), IL-1β (I) and IL-6 (J) detected by ELISA. Data are expressed as mean ± SD (n = 6/group), # indicates p<0.05 (vs. Sham group), * indicates p<0.05 (vs. CLP group).