Research Paper Volume 15, Issue 17 pp 8729—8743
Uncovering the pathogenesis of obesity complicated with papillary thyroid carcinoma via bioinformatics and experimental validation
Figure 6. Experimental validation of hub genes. (A–D) MNDA, TNC, CHIT1 and MMP9 were found to be highly expressed in patients’ serum with obesity combined with PTC ((A) P < 0.01, (B) P < 0.05, (C) P < 0.01, (D) P < 0.001). (E–I) The expression of four hub genes in the patient tissues and the normal tissues (F) patient1: P < 0.01, patient2: P < 0.01, patient3: P < 0.01; (G) patient1: P < 0.01, patient2: P < 0.05, patient3: P < 0.05; (H) patient1: P < 0.01, patient2: P < 0.01, patient3: P < 0.05; (I) patient1: P < 0.01, patient2: P < 0.01, patient3: P < 0.05). P < 0.001 was denoted as “***”, P < 0.01 as “**”, P < 0.05 as “*”, and P > 0.05 as “ns”.