Research Paper Volume 15, Issue 19 pp 10089—10104
Eriocitrin inhibits epithelial-mesenchymal transformation (EMT) in lung adenocarcinoma cells via triggering ferroptosis
Figure 2. Eriocitrin treatment strongly inhibited the EMT process of A549 and H1299 cells via abrogating Snail expression and inhibited the invasion. (A, B) The transwell assay of A549 and h1299 cells and quantitative count after eriocitrin treatment 24 h at 50 μM concentration. (C–F) The protein expression of EMT-related genes after eriocitrin treatment 24 h in A549 and H1299 cells. (G–I) The mRNA expression of E-cadherin, N-cadherin, Snail in A549 and H1299 cells after eriocitrin treatment 24 h at 50 μM concentration. *P < 0.05, **P < 0.01, and ***P < 0.001.