Research Paper Volume 15, Issue 20 pp 11227—11243

Electroacupuncture pretreatment protects against anesthesia/surgery-induced cognitive decline by activating CREB via the ERK/MAPK pathway in the hippocampal CA1 region in aged rats

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Figure 3. EA pretreatment alters the gene expression profile in the hippocampal CA1 region of POCD aged rats. (A) Differential gene volcano map. (B) Heatmap of differential gene cluster analysis. (C) GO enrichment analysis pathways. (D) GO enrichment analysis of synaptic pathways. (E) KEGG pathway enrichment scatter diagram. (F) GSEA gene enrichment analysis diagram of the MAPK signaling pathway.