CDKN2A was a cuproptosis-related gene in regulating chemotherapy resistance by the MAGE-A family in breast cancer: based on artificial intelligence (AI)-constructed pan-cancer risk model

Hong Wan; Xiaowei Yang; Guopeng Sang; Zhifan Ruan; Zichen Ling; Mingzhao Zhang; Chang Liu; Xiangyang Hu; Tao Guo; Juntong He; Defeng Liu; Jing Pei

doi:doi:10.18632/aging.205125

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Research Paper Volume 15, Issue 20 pp 11244—11267

CDKN2A was a cuproptosis-related gene in regulating chemotherapy resistance by the MAGE-A family in breast cancer: based on artificial intelligence (AI)-constructed pan-cancer risk model

Figure 11. Drug sensitivity prediction in CRG subgroups. The OncoPredict function in R4.2.0 is performed to predict drug scores in four cohorts, and they are the (A) GEO breast cancer cohort (combined with GSE20685, GSE58812, GSE42568; n=538), (B) the TCGA breast cancer cohort (n=1089), (C) the GEO TNBC cohort (combined with GSE18864, GSE58812, GSE76124, GSE83937, GSE95700; n=517), and (D) the large GEO breast cancer cohort (combined with 16 independent cohorts; n=2953).