Research Paper Volume 16, Issue 2 pp 1808—1828

Identification of BANF1 as a novel prognostic biomarker in gastric cancer and validation via in-vitro and in-vivo experiments

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Figure 9. Knockdown of BANF1 inhibited tumor growth in in vivo experiments. (A) Photographs of nude mice injected with BANF1 knockdown MKN-45 (n = 6) and blank control MKN-45 cells (n = 6). (B) Photographs of subcutaneous tumors of nude mice in the knockdown group (n = 6) and control group (n = 6). (C, D) Comparison of subcutaneous tumor volume and weight of nude mice in knockdown and control groups. (E) Immunohistochemical staining of Ki67 in subcutaneous tumors of nude mice. (F) TUNEL staining of subcutaneous tumors in nude mice. All experiments were repeated at least three times. **p < 0.01, ***p < 0.001.