Research Paper Volume 16, Issue 4 pp 3531—3553

Senescence-related genes analysis in breast cancer reveals the immune microenvironment and implications for immunotherapy

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Figure 4. Identification of the reliability of the model. (AD) The ROC curve of patients’ survival over different years in the training, testing, all, and GEO cohort showed that the model had a potent predicting ability. (E, F) Univariate and Multivariate Cox regression revealed that the risk score was an independent prognostic factor in BRCA patients. (G) Nomogram for predicting overall survival. (H) The calibration curves for 1-,3-, and 5-year OS. (IL) The PCA 3D scatterplot of sample distribution is based on all genes, senescence-related genes, and model senescence-related genes in TCGA and GEO, respectively.