Research Paper Volume 16, Issue 4 pp 3750—3762

Suppression of cerebral ischemia injury induced blood brain barrier breakdown by dexmedetomidine via promoting CCN1

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Figure 3. Dex remarkably improved the memory ability and neurological function of MCAO rats. (A) Morris water maze test was performed to evaluate the influence of Dex and sh-CCN1 on memory ability of rats (n = 5); (B) Escape latency was analyzed; (C) Swim distance was calculated; (D) The neurological function was evaluated with neurological severity score; (E) The neurological function was evaluated with Longa score. *p < 0.05. n = 5.