Research Paper Volume 15, Issue 14 pp 6921—6932
Exosomal lnc-CDHR derived from human umbilical cord mesenchymal stem cells attenuates peritoneal epithelial-mesenchymal transition through AKT/FOXO pathway
Figure 4. hUMSC-CM improves HG-induced peritoneal EMT via exosomes. (A, B) Expression of EMT markers (α-SMA, Vimentin, and E-cadherin) in HMrSV5 was detected by WB and PCR after hUMSC-CM and hUMSC-Exos treated HMrSV5 which was stimulated by HG. (C, D) The expression of miR-3149 and lnc-CDHR was detected by PCR. Each value represents the mean ± SEM (n=3) (**P<0.01 vs. Control, ##P<0.01 vs. HG, #P<0.05 vs. HG).