Research Paper Volume 15, Issue 19 pp 10105—10116

SNHG25 promotes colorectal cancer metastasis by regulating MMP2

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Figure 3. SNHG25 regulates CRC cells metastasis. (A) The migration and invasion abilities of HCT-116 and HT-29 cells were evaluated using transwell assays. (B) Representative images of wound healing assays performed using HCT-116 and HT-29 cells after SNHG25 silenced. (C) The expression of Vimentin and E-Cadherin were examined by western blot in SNHG25 knockdown HCT-116 and HT-29 cells. (D) The expression of Vimentin and E-Cadherin were detected by immunofluorescence after SNHG25 silencing. *P < 0.05, **P < 0.01 and ***P < 0.001.