Research Paper Volume 15, Issue 23 pp 13646—13654
Cabozantinib prevents AGEs-induced degradation of type 2 collagen and aggrecan in human chondrocytes
Figure 1. Cytotoxicity of Cabozantinib in SW1353 chondrocytes. (A) Molecular structure of Cabozantinib; (B) Cells were stimulated with Cabozantinib at the concentrations of 0, 1.25, 2.5, 5, 10, 20, 40, 80 μM for 24 hours. The cell viability was measured using the MTT assay (n=6, *, ** P<0.05, 0.01 vs. Control group).