Research Paper Volume 15, Issue 23 pp 13854—13864
Long noncoding RNA MEG8 induces an imbalance of Th17/Treg cells through the miR-107/STAT3 axis in Henoch-Schonlein purpura rats
Figure 5. The relative luciferase function of miR-107, MEG8 and STAT3 expression in RAOEC cells. (A) The MEG8 WT and MEG8 Mut in bonding locations for MEG8/miR-107. (B) The miR-107 WT and miR-107 Mut of bonding locations for MEG8/miR-107. (C) The STAT3 WT and STAT3 Mut. (D) miR-107 WT and miR-107 Mut. (E) miR-107 and STAT3 expression, and (F) STAT3 proteomic content in control CD4+ T cells transfected with the miR-107 mimic, mimic NC, miR-107 inhibitor, and inhibitor NC. *P <0.01 vs. mimic NC group; ※P <0.01 vs. inhibitor NC group.