Research Paper Volume 15, Issue 23 pp 13888—13900
HACE1 expression in heart failure patients might promote mitochondrial oxidative stress and ferroptosis by targeting NRF2
Figure 5. Sh-HACE1 could promote heart failure in mice model. CK and LDH activity levels (A, B), heat tissue injury (Masson and HE staining, C), left ventricular internal diameter (D), heat tissue injury (Masson and HE staining (E), left ventricular ejection fraction (F), left ventricular fractional shortening (G), left ventricular stroke volume (H), MDA/SOD/ GSH/GSH-PX levels in heat tissue (I–L) ##p<0.01 compared with model+vector group.