Research Paper Volume 15, Issue 24 pp 14915—14929

hsa_circ_0002980 prevents proliferation, migration, invasion, and epithelial-mesenchymal transition of liver cancer cells through microRNA-1303/cell adhesion molecule 2 axis

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Figure 3. circ_0002980 overexpression markedly weakened the migration, invasion, and EMT of LC cells. (A) We adopted Transwell assays to identify the impact of circ_0002980 overexpression on the migration and invasion capacities of LC cells. Magnification, 200×. (B) The levels of EMT-related proteins (Fibronectin, Vimentin, E-cadherin, and β-Catenin) were analyzed by applying Western blot in circ_0002980-overexpressed LC cells. (C) Western blotting results were quantitatively analyzed. **P < 0.01; ***P < 0.001.