Research Paper Volume 15, Issue 24 pp 15228—15242

Causal effects of lipid-lowering therapies on aging-related outcomes and risk of cancers: a drug-target Mendelian randomization study

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Figure 2. Forest plot visualizing the causal effects of the genetically proxied lipid-lowering drug targets on longevity-related traits. The forest plot showed the estimated effects of 1 mmol/L lower LDL-C or TG concentration by target-specific variants in each drug target gene on longevity-related traits, using the IVW method. Beta and 95% CI were used in quantitative outcomes.