Research Paper Volume 15, Issue 24 pp 15599—15623

Unravelling diagnostic clusters and immune landscapes of cuproptosis patterns in intervertebral disc degeneration through dry and wet experiments

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Figure 6. Consensus clustering of the 8 significant cuproptosis modulators in IDD. (AD) Consensus matrices of the 8 significant cuproptosis modulators for k = 2–5. (E) Expression heat map of the 8 significant cuproptosis modulators in clusterA and clusterB. (F) Differential expression boxplot of the 8 significant cuproptosis modulators in clusterA and clusterB. (G) GO analysis that explores the potential mechanism underlying the effect of the 163 cuproptosis-related DEGs on the occurrence and development of IDD. *p < 0.05, **p < 0.01, and ***p < 0.001.