Research Paper Volume 15, Issue 24 pp 15599—15623
Unravelling diagnostic clusters and immune landscapes of cuproptosis patterns in intervertebral disc degeneration through dry and wet experiments
Figure 8. Consensus clustering of the 163 cuproptosis-associated DEGs in IDD. (A–D) Consensus matrices of the 163 cuproptosis-associated DEGs for k = 2–5. (E) Expression heat map of the 163 cuproptosis-associated DEGs in gene clusterA and gene clusterB. (F) Differential expression boxplot of the 8 significant cuproptosis modulators in gene clusterA and gene clusterB. (G) Differential immune cell infiltration between gene clusterA and gene clusterB. (H) Differences in cuproptosis score between clusterA and clusterB. (I) Sankey diagram showing the relationship between cuproptosis patterns, cuproptosis gene patterns, and cuproptosis scores. *p < 0.05, **p < 0.01, and ***p < 0.001.