Research Paper Volume 16, Issue 3 pp 2715—2735
Integrated single-cell and bulk characterization of branched chain amino acid metabolism-related key gene BCAT1 and association with prognosis and immunogenicity of clear cell renal cell carcinoma
Figure 2. The immune characteristic of the BCAA metabolism-related clusters. (A) Distribution of immune infiltrating cells and tumor microenvironment scores between BCAA metabolism-related clusters. (B) Differential abundance of immunosuppressive cell infiltration (Macrophage, Regulatory.T.cell, and Myeloid-derived suppressor cells (MDSC)) between BCAA metabolism-related clusters. (C) Differences in the 13 immune-related functions between BCAA metabolism-related clusters. (D) Differential expression of immunosuppressive checkpoints between BCAA metabolism-related clusters. Wilcox test was used, and the asterisks represent the statistical P-value (*p <0.05, ** p <0.01, *** p <0.001).